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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
23.64
Human Site:
S17
Identified Species:
40
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
S17
W
V
Q
D
E
L
H
S
V
L
G
L
S
E
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S17
W
V
Q
D
E
L
H
S
V
L
G
L
S
E
R
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
S17
W
V
Q
D
E
L
H
S
V
L
G
L
S
E
R
Dog
Lupus familis
XP_538827
1042
119346
S17
W
V
Q
D
E
L
H
S
V
L
G
L
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
N40
K
V
C
T
E
L
D
N
H
L
G
I
N
D
K
Rat
Rattus norvegicus
NP_997661
1044
119245
S17
W
V
Q
E
E
L
H
S
V
L
G
L
S
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
G28
R
L
G
R
C
Y
R
G
A
R
G
L
C
T
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
F26
S
D
R
Y
V
A
Q
F
M
I
G
L
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
S14
K
R
T
A
S
S
S
S
S
G
E
E
P
D
S
Honey Bee
Apis mellifera
XP_001122325
831
95330
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
Y25
S
D
R
S
I
C
Q
Y
V
H
A
L
A
K
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
T24
N
V
C
N
E
L
E
T
H
L
G
S
A
E
K
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L43
F
I
R
N
I
Q
K
L
D
A
G
I
S
Y
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
100
100
100
N.A.
33.3
93.3
N.A.
N.A.
20
N.A.
13.3
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
66.6
100
N.A.
N.A.
26.6
N.A.
46.6
N.A.
13.3
0
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
8
8
8
0
15
0
0
% A
% Cys:
0
0
15
0
8
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
15
0
29
0
0
8
0
8
0
0
0
0
15
0
% D
% Glu:
0
0
0
8
50
0
8
0
0
0
8
8
0
43
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
8
72
0
0
0
0
% G
% His:
0
0
0
0
0
0
36
0
15
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
15
0
0
0
0
8
0
15
0
0
0
% I
% Lys:
15
0
0
0
0
0
8
0
0
0
0
0
0
8
29
% K
% Leu:
0
8
0
0
0
50
0
8
0
50
0
58
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
36
0
0
8
15
0
0
0
0
0
0
8
0
% Q
% Arg:
8
8
22
8
0
0
8
0
0
8
0
0
0
0
43
% R
% Ser:
15
0
0
8
8
8
8
43
8
0
0
8
43
0
8
% S
% Thr:
0
0
8
8
0
0
0
8
0
0
0
0
0
8
0
% T
% Val:
0
50
0
0
8
0
0
0
43
0
0
0
8
0
0
% V
% Trp:
36
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _